2018 Cutaneous Biology

Dr Tobias Bald

Dr Tobias Bald is an international Fellow and Team Head in the Department of Immunology at QIMR Berghofer Medical Research Institute. He obtained his PhD in Molecular Biomedicine at the University of Bonn, where he received training in tumour immunology and tumour biology. In the last years Dr Bald focused on the balance between anti-tumour immunity and pro-tumorigenic inflammatory responses using genetically engineered mouse models which portray the clinical situation of melanoma patients. Dr Bald could show that targeted activation of the type I IFN system with immunostimulatory RNA in combination with blockade of immune inhibitory receptors serve as a rational strategy to expose immune cell-poor melanomas to cellular immune surveillance. Furthermore, he established and characterized novel genetically engineered mouse melanoma models to experimentally investigate the interaction between innate immune, endothelial and melanoma cells. Currently, Dr Bald is studying the immunosuppressive role of innate immune cells during tumour development and immunotherapy.

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